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吸入毒理学：行政途径
Although oral drug administration is the most common type of drug delivery, many patients prefer inhaled medicines, if possible, over injections or other more invasive delivery methods. Inhalation toxicology studies are becoming vital in assessing the safety and potential toxicity of inhaled drugs or chemicals asrespiratory diseasesincluding asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) also become more common.
- 每年进行超过150项吸入研究
- 雾化工程能力
- 专用吸入设施
- Regulatory experience with inhaled medicines,肺部疾病and医疗设备
- 视图respiratory pharmacology & pharmacodynamic (PD) models。
- 学习关于yaboapp体育官网临床前至市场后呼吸治疗症的解决方案。
Why You Might Want to Consider the Inhalation Route
- 患者易用性=更好地采用和遵守。吸入的药物优选注射或其他侵入性方法。
- 快速吸毒。肺的渗透膜允许快速给药和快速代谢到身体中以治疗快速发病症状。
- Reduced cost impact on the healthcare system.掌上电脑和测量剂量吸入器都是标准的医疗技术，员工和家庭患者都已经熟悉，使其对医疗保健系统的低障碍和低成本影响。
- New generation of inhaler devices and techniques.The 3rd generation of devices can now include engineered products, which can potentially reduce the drug volume needed to reach efficacy as well as side effects.
- 技术设备进步。New devices have made impressive gains, including electronic feedback, volume monitoring, electrostatic charging, specialized nano-carriers and humidity / temperature compensated delivery.
- 设备专利可能会延长产品寿命。即使在制药专利到期后，您也可以从设备上受益。
在设计吸入研究之前要问的重要问题
What to Expect From Covance Inhalation Capabilities
Less test material = more cost savings
Test material is expensive to manufacture. We've miniaturized toxicology delivery systems to最大限度地减少材料损失通过气流量，设计了一套3d面部面具to prevent leakage and developed techniques toenhance the bioavailability测试项目，需要较低的剂量。
综合和组合发展经验
As a full-service CRO, you'll have access to efficacypharmacology models for respiratory那呼吸临床试验，这设备开发团队for a drug/device combo, and the市场访问团队，熟练帮助您了解药物设备组合的复杂定价策略。
专门的支持团队
从我们旨在的吸入毒理学设施和in-house aerosolization engineering我们世界知名的科学工作人员和专门的吸入研究董事的能力more than 150 inhalation studies annually，您和您的化合物将得到很好的支持。符合我们的一些吸入科学家：
