Custom Antibody Reagents
Providing you with an end-to-end service to generate antibody reagents against a variety of antigen types in a broad range of host species.
Custom Antibody Capabilities
For nearly five decades, we’ve been refining services and capabilities to help you manage the entire antibody development process.
Choose from a comprehensive set of suite of services including:
- Polyclonal & monoclonal antibody production
- Purification, labeling and characterization of antibodies
- Hybridoma generation, characterization and scale-up of non-GLP assay qualification and sample analysis
Tool Antibody Reagents
Tool antibody reagents are standard antibody generation services for use in characterization of the target in basic/academic settings or exploratory drug discovery research.
Critical antibody reagents are used in a regulated drug development setting and include both polyclonal and monoclonal anti-drug antibodies, anti-idiotypic antibodies and anti-host cell protein antibodies. These reagents are generated with extensive documentation, additional levels of characterization and often larger quantities to last for the duration of the product's lifecycle.
A full range of production services are available in diverse rodent strains. You can choose in vivo或在体外生产协议和适应的公关otocols for small or large quantities depending on your needs.
As leading providers in custom anti-ID antibody development, our teams will bring unique scientific expertise to your anti-ID project such as:
By partnering with us, you will benefit from our extensive capabilities in generating capture reagents forPK/TK studies中和试验和抗原显像阳性对照。
Generate hybridomas against a large array of antigens and keep all cell lines developed by Covance as your exclusive property. Also, all four hybridoma development stages – immunization, fusion and screening, subcloning and clone stabilization – are customizable.
With extensive in体外/体内放大能力，以适应任何规模的项目，您可以体验到一系列额外的免疫服务。这些包括细胞系扩增、PBMC分离、同型和支原体检测。
Anti-Host Cell Protein Antibodies (Anti-HCP)
We can help you every step of the way, with our custom reagent and method development for anti-HCP assays:
- Custom reagent and method development
- 分析开发/瓦里dation (ELISA)
By partnering with leading providers of custom ADA development, you will benefit from our scientific expertise across the development process as well as our extensive capabilities in custom reagent development and related ADA services, including development of PK, TK, and potency assays.
Our key skills involve generating positive control for PK/TK studies and capture reagents for potency assays. We have a dedicated immunochemistry lab providing protein A/G and/or antigen-specific purifications, along with various options for depleting cross-reactive antibodies.
- Various adjuvants