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At Covance, our dedicated cardiovascular specialists have a unique combination of both academic and industry experience that provides you with insightful study design, predictive study management and operational service excellence. Maximize your cardiovascular drug development program with Covance's experience and cross-functional solutions.

As you move to high stakes phase IIb clinical trials and phase III clinical development, you’ll benefit from our end-to-end suite of services.

将您的临床和经济证明放在一起（POC®），以最大限度地提高分子的价值，以使您的药物发达于市场。

Covance提供市场访问咨询，旨在探索您的产品潜力。

Working together, we will remove barriers, build relationships and gain insights as your product reaches the real world of patients and providers.

Covance免疫学服务。完全综合的免疫治疗药物开发能力，可为更好的投资回报率。

Covance帮助罕见的疾病和孤儿药companies find and identify specific rare disease patients to meet challenging recruitment goals and run rare disease clinical trials. With Covance, you’ll access a combination of dedicated rare disease therapeutics expertise alongside comprehensive operational support to assist with every aspect of your orphan drug clinical study.

The absorbance of the solution is measured by a UV-visible spectrometer. The Beer-Lambert Law uses the terms absorbance and molar absorptivity relating to UV-visible absorption spectrometry. The absorbance for a molar concentration of a substance with a path length of 1 cm determined at a specific wavelength is obtained from the equation ε = A / cl.

ACD/Percepta molecular property prediction software provides a platform for calculating physicochemical, ADME and toxicology properties from the chemical structure of a given compound. Four key offerings of the software are: molecular properties from structure, name or SMILES string can be predicted, single interface for a complete portfolio of property predictions, visual aid via sub-structure highlighting and user-friendly plotting/sorting/ranking of results.

这是一种自动化的非标准测定，测量乙酰胆碱酯酶（ACHE）的水平，以支持药物开发研究。有关研究模式功能，请与我们联系以获取特定网站的详细信息。分析疼痛抑制作用于药物发现中的特定生物标志物，以确定化合物是否是疼痛抑制剂。

The 5-batch analysis testing is a requirement prior to registration of a pesticide in the agrochemical sector. At least 5 separate production batches, or intervals in a continuous process, need to be tested for the amount of active ingredient and for the level of any impurities over and above 1 g/kg. The analysis is carried out in accordance with good laboratory practice (GLP) standards and the results must account for ≥98% of the material tested.

This is one of three coagulation/hemostatis assays to measure clotting and is an automated plasma analysis, supporting translational research studies. Activated partial thromboplastin time (aPTT) monitors the extrinsic and common pathways. Prolonged aPPT tests means clotting is taking longer and this may be due to a range of factors, so further tests may need to be undertaken. Also see: Fibrinogen (FIB). Prothrombin time (PT)

An acute renal occlusion procedure for in vivo models generates a template for human ischemic acute renal failure (ARF). Typically using reversible rat and mouse models, the ischemic tubular damage is produced by complete occlusion of the renal artery for various time periods. Despite some functional similarities between the model and human ARF (e.g., decrease in GFR), there are also questionable differences, such as more extensive necrosis of proximal tubules in the animal model.

Acute Toxicity Studies evaluate short-term serious adverse effects after clinical and parenteral administration either as a single dose or in multiple doses during 24 hours. The test uses two mammalian species, including one non-rodent, and provides the following information: Potential for acute toxicity in humans Potential for toxicity against the target organs The time course of drug-induced effects An appropriate dosage for multiple-dose toxicity studies Species differences in toxicity...

用于显影和验证GLP免疫原性测定的多克隆和单克隆抗药物抗体阳性对照。

ADME studies investigate the absorption, distribution, metabolism and excretion (ADME) of a radiolabeled compound. The route of administration is often identical to the intended clinical route of administration (pharmaceutical), the intended application (veterinary), or to support the safety evaluation of an agricultural protection product. Intravenous administration is also often included, where possible, to allow assessment of the absolute bioavailability of the test material....