配制产品的物理化学性质和技术特征

作物保护

Formulated products also need characterization. Formulations are mixtures that contain one or more active ingredient as well as other ingredients. Formulations may be solids, such as dusts, granules or pellets, wettable products that require combination with a liquid (usually water), liquids such as emulsions or solutions, or aerosols and fumigants, which are gases. Formulations are tested for active ingredient content, impurities and other entities such as stabilizers or emulsifiers. The tests conducted on formulations depend on the formulation type, nature of the product, the application concentrations, the number and identity of active ingredients, and the analytical methods available.

需要以特定方式制备和应用不同类型的制剂。理解制剂的技术特征可以识别可能的处理和应用问题,例如,与涂抹器暴露或诸如混合时过度发泡的诸如过度发泡的风险。它们还可以在评估所需的终点方面构成独特的挑战。

Physicochemical_properties
  • 目的建造设施,以满足各种温度的储存,以满足国家特定要求
  • Expertise in development of analytical methodology to enable quantification of all components within each formulation
  • Track record of performing successful accelerated and long-term storage stability tests

Your Needs

How to approach testing for formulated agrochemical products

Active ingredients are used in formulations that contain other ingredients such as emulsifiers. The presence of these additional chemicals and the nature of the formulation can pose specific challenges for physicochemistry testing. Selecting appropriate validated analytical methods is one critical aspect and much depends on the formulation itself. Understanding the potential pitfalls is key to designing an appropriate testing strategy.

有很多事情需要考虑:你如何determine the best way of establishing technical characteristics? What is required for different types of products, pesticides, conventionals, biopesticides and biocides? What endpoints are needed for different types of formulations? How do you handle different formulations for test purposes? What duration is appropriate for stability assessment of your formulation? How does the stability of individual elements in the formulation change with temperature, light or humidity, and how does this influence stability test design?


Our Capabilities

所有类型的农药产品配方体验

Covance拥有各种杀虫剂的经验;常规的除草剂,杀菌剂和杀虫剂和杀生物产品 - 以及所有类型的配方;固体,液体和气体。我们已经使用了许多难以处理的材料,例如不溶性分子和UVCB。这种经验使我们在制剂的技术表征方面具有巨大的科学洞察力和实践专业知识。

Standard physicochemical tests for formulated plant protection products

配制产品需要各种物理化学测试。这些取决于配方的类型。可用标准测试(但不限于)包括:

  • Persistent Foaming
  • 相对密度
  • Bulk and tap density
  • Viscosity)
  • 对金属的腐蚀
  • Low temperature stability
  • 出现
  • pH and Acidity/Alkalinity
  • Dilution Stability
  • 暂停
  • Sponteneity

Hazardous properties testing for formulated products

配制产品需要一系列危险的终点测试;有些类似于活性成分的物质。可以根据结构警报和处理类似测试制剂的经验来评估这些终点。危险性能测试包括:

  • 爆炸性质
  • 氧化特性
  • Self-reactive substances
  • Flammability Studies
  • 发火特性
  • 有机过氧化物

Identification of technical characteristics for formulated products

The tests used for technical characterizations of formulated products depends on the formulation and the type of product. Our suite of tests covers the following endpoints for conventional pesticides including:

  • 润湿性
  • 暂停, spontaneity and dispersion stability
  • Wet sieve and dry sieve
  • Emulsion stability
  • Disintegration time
  • Particle size, dust content and attrition, friability
  • Persistent foaming
  • 流动性,可倾倒性和防尘
  • 燃烧率

For biocidal product formulations, some alternative tests may be required for endpoints including:

  • 喷涂图案
  • 物理和化学兼容性
  • Degree of dissolution and dilution stability

存储稳定性测试适合您的需求

我们的设施通过不同的湿度,光和温度在一系列条件下进行测试。Covance可以执行加速或长期储存稳定性测试,取决于产品和配方:

  • 根据活性成分或共配方的稳定性,在各种温度和持续时间内进行加速试验
  • 长期存储试验在环境温度(通常为25°C),通常为2年

对于两个测试,在每个时间点执行有效成分分析。为了复制现实生活,可以在可能的情况下存储样品。