Real World Evidence (RWE)helps payers make reimbursement decisions and assists patients in budget management and estimating risk benefit of interventions. The integration of RWE in value assessment frameworks, used for ascertaining drug value, can help payers make informed evidence-based reimbursement decisions. RWE provides insight into real world impact of an intervention; facilitating “performance-based risk-sharing arrangements” between payers and manufacturers. United Health and Merck have collaborated to link payments to drug performance by utilizing RWE. Similarly, Amgen and Humana have partnered to target chronic diseases by generating RWE.
Patient engagement is another core component for RWE generation as well as its dissemination. Prescription Drug User Fee Act (PDUFA) re-authorization and the 21st Century Cures Act emphasize the use of patient data for drug development. Patients can make better-informed health decisions based on information from Patient-Centered Outcomes Research Institute, National Health Council, virtual networks and digital technology like mHealth. Johnson & Johnson collaborated with Aetna to use wearable technology in atrial fibrillation screening for RWE generation. Health PROMISE, a patient reported outcome tool integrated with EHRs, helped IBD patients and providers to visualize real time data; thus improving their quality of life.
结论
现实世界的证据可以帮助付款人和患者通过现实世界患者数据评估干预的成本效益分析。创新使用技术可以表现出提高患者参与的前进和创造机会，以创造访问，整合，分析和有效利用RWE的机会。
